Plasma p-Tau-217 Assays Work Well, But No Home Run for Diagnosis

from AlzForum

• In round-robin, p-tau217 flies into the lead.

• Accuracies fall just shy of what’s needed for a stand-alone test.

• Using two cut points could close the gap.

Feel like your head is spinning? Like a little blood sample in a centrifuge, perhaps? No need to panic. It just means you are straining, like the rest of us, to keep up with the Alzheimer's disease plasma biomarker development field. New markers, new assays, new protocols seem to arrive at a dizzying pace. A flurry of those was on display at this year’s CTAD meeting, held last month in Boston. “The field is moving very rapidly,” noted Andreas Jeromin, ALZpath Inc.